Active ingredient: Naproxen 250mg

Also contains lactose.

On the first day TWO tablets (500 mg) should be taken initially and then ONE tablet (250 mg) after 6 to 8 hours if needed. On the second and third day, if required, ONE tablet (250mg) should be taken every 6 to 8 hours. Not more than 3 tablets to be taken per day and for no longer than 3 days

For women between 16 and 50 years old:

Take this medication with or after food, swallowed whole with water. Tablets should not be broken or crushed.

On the first day take 2 tablets (500mg) and then one tablet (250mg) after 6 to 8 hours, only if needed.

On the second and third day, if needed, take one tablet (250mg) every 6 to 8 hours.

Not more than 3 tablets to be taken per day.

The maximum duration of continuous treatment in any one cycle (period) is 3 days.

If symptoms are persistent and do not respond to the initial treatment please consult your GP.

• If you are a man
• If you are under 16 years of age or over 50 years of age
• If your symptoms are severe
• If allergic to naproxen, naproxen sodium formulations or any of the excipients
• If you are pregnant or think you might be pregnant
• If you are breastfeeding
• If you currently have or have had peptic ulceration and active gastrointestinal bleeding
• If you have experienced bleeding or perforation, related to previous NSAIDs therapy with ibuprofen, naproxen, aspirin or similar medications)
• If aspirin, ibuprofen or other non-steroidal anti inflammatory/analgesic drugs induce the syndrome of asthma, rhinitis, nasal polyps, angioedema, urticaria or other hypersensitivity reactions
• If you have congestive heart failure, established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease
• If you have liver or kidney problems
• If you have any cardiac impairment
• If you have moderate or severe hypertension
• If you have mild uncontrolled hypertension
• If you have a history of gastro-intestinal disease
• If you have a rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption
• If you have difficulties conceiving, are undergoing investigation of fertility or are attempting to conceive
• If you first experienced period pain more than a year after starting menstruation
• If you have or think you might have a sexually transmitted infection
• If your period pain is caused by something else (i.g endometriosis)
• If you have any coagulation disorders
• If you are at high risk of bleeding

Do not take this treatment if you are currently taking any of the following medications:

̵ Naproxen-containing products
̵ Oral corticosteroids
̵ Anticoagulants or other coumarin derivatives
̵ Heparin
̵ Selective serotonin-reuptake inhibitors or anti-platelet agents
̵ Other NSAIDs including (e.g. ibuprofen, cyclooxygenase-2 selective inhibitors, aspirin)

As for all medication, Naproxen can cause side effect. Undesirable effects may be minimised by using the lowest effective dose for the shortest duration necessary to control symptoms. If you are treated with NSAIDs long-term, you should undergo regular medical supervision to monitor for adverse events:

Severe hepatic reactions, including jaundice and hepatitis
Naproxen decreases platelet aggregation and prolongs bleeding time
Exacerbation of bronchospasm, asthma or allergic desease
Kidney toxicity
Fluid retention, hypertension and oedema
Increase in blood pressure
Gastrointestinal (GI) bleeding that can often manifest as really dark, black stools.
If you experience anny of the above symtpoms, stop taking the medication and seek immediate medical advice.